MRT6160 chemical structure
Chemical structureResearch use only
CAT. NO. DC60676Featured

MRT6160

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TotalUS$650
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Product overview

Description & Application

MRT-6160 represents a groundbreaking molecular glue degrader designed to selectively target VAV1, achieving its proteasomal degradation with a DC50 value of 7 nM. This innovative compound showcases its unique mechanism and therapeutic potential.

ParameterValue
Chemical NameVAV1 degrader-3
CAS No.3050683-38-7
Synonyms3050683-38-7;VAV1 degrader-3;EX-A11887
FormulaC22H17ClN2O3
M.Wt392.83
SMILESClC1C(=CC=CC=1C1C(NC(CC1)=O)=O)C1C=CC(=CC=1)N1C=CC=CC1=O
Purity98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

MRT-6160 represents a groundbreaking molecular glue degrader designed to selectively target VAV1, achieving its proteasomal degradation with a DC50 value of 7 nM. This innovative compound showcases its unique mechanism and therapeutic potential.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Solution calculator

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