C18 NC-TNP
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
Si12-C10 is a siloxane-incorporated lipid for spleen-targeting mRNA delivery. The siloxane moieties enhance cellular internalization of mRNA-LNPs and improve their endosomal escape capacity, augmenting their mRNA delivery efficacy.
| CAS No. | Not available |
| Chemical Name | Si12-C10 |
| Synonyms | Si12 C10, Si12C10 |
| SMILES | CCCCCCCCC(O)CN(CCSCC[Si]1(C)O[Si](C)(CCSCCN(CC(O)CCCCCCCC)CC(O)CCCCCCCC)O[Si](C)(CCSCCS(=O)(=O)O)O1)CC(O)CCCCCCCC |
| Formula | C55H118O10N2S4Si3 |
| M.Wt | 1,180.05 |
| Purity | >98% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 8.4742 mL | 1.6948 mL | 847.42 μL |
| 25 mg | 21.1855 mL | 4.2371 mL | 2.1186 mL |
| 50 mg | 42.3711 mL | 8.4742 mL | 4.2371 mL |
| 100 mg | 84.7422 mL | 16.9484 mL | 8.4742 mL |
| 250 mg | 211.8554 mL | 42.3711 mL | 21.1855 mL |
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