A1120 chemical structure
Chemical structureResearch use only
CAT. NO. DC39004Featured

A1120

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TotalUS$550
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Product overview

Description & Application

A 1120 is a high affinity non-retinoid ligand for retinol-binding protein 4 (RBP4) with the ki value of 8.3 nM[1].

ParameterValue
Chemical Name2-(4-(2-(Trifluoromethyl)phenyl)piperidine-1-carboxamido)benzoic acid
CAS No.1152782-19-8
SynonymsA-1120, A1120, 2-(4-(2-(Trifluoromethyl)phenyl)piperidine-1-carboxamido)benzoic acid
FormulaC20H19F3N2O3
M.Wt392.3782
SMILESO=C(NC3=C(C(O)=O)C=CC=C3)N1CCC(C2=C(C(F)(F)F)C=CC=C2)CC1
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

A 1120 is a high affinity non-retinoid ligand for retinol-binding protein 4 (RBP4) with the ki value of 8.3 nM[1].

In Vitro

The IC50 of A 1120 is 90 nM on human RBP4 and 66 nM on mouse RBP4[1].

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

Target

ki: 8.3 nM (Retinol-binding protein 4)[1]

References & source

[1]. Motani A, et al. Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivo. J Biol Chem. 2009 Mar 20;284(12):7673-80.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

Refer to the certificate supplied with your lot for batch-specific release results.

Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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