Biological Activity
A 1120 is a high affinity non-retinoid ligand for retinol-binding protein 4 (RBP4) with the ki value of 8.3 nM[1].
In Vitro
The IC50 of A 1120 is 90 nM on human RBP4 and 66 nM on mouse RBP4[1].
In Vivo
No in vivo data are provided in the current product source. Contact us for further information.
Target
ki: 8.3 nM (Retinol-binding protein 4)[1]
References & source
[1]. Motani A, et al. Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivo. J Biol Chem. 2009 Mar 20;284(12):7673-80.
Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.