Cedazuridine chemical structure
Chemical structureResearch use only
CAT. NO. DC20987Featured

Cedazuridine

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TotalUS$650
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Product overview

Description & Application

Cedazuridine (E7727) is a Cytidine Deaminase (CDA) inhibitor with an IC50 value of 0.4 μM[1].

ParameterValue
Chemical NameCedazuridine
CAS No.1141397-80-9
SynonymsE7727;E-7727;E 7727
FormulaC9H14F2N2O5
M.Wt268.217
SMILESO=C1N([C@H]2C(F)(F)[C@@H]([C@@H](CO)O2)O)CC[C@@H](O)N1
Purity>95%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Cedazuridine (E7727) is a Cytidine Deaminase (CDA) inhibitor with an IC50 value of 0.4 μM[1].

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

Target

Cytidine Deaminase (CDA) :IC50: 0.4 μM (CDA)[1]

References & source

[1]. Ferraris D, et al. Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase. J Med Chem. 2014 Mar 27; 57(6):2582-8.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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