Cedazuridine Datasheet | DC20987

Cedazuridine — Datasheet

CAT. NO. DC20987

Parameter	Value
Chemical Name	Cedazuridine
CAS No.	1141397-80-9
Synonyms	E7727;E-7727;E 7727
Formula	C9H14F2N2O5
M.Wt	268.217
SMILES	O=C1N([C@H]2C(F)(F)[C@@H]([C@@H](CO)O2)O)CC[C@@H](O)N1
Purity	>95%
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Cedazuridine (E7727) is a Cytidine Deaminase (CDA) inhibitor with an IC50 value of 0.4 μM[1].

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

Target

Cytidine Deaminase (CDA) :IC50: 0.4 μM (CDA)[1]

References & source

[1]. Ferraris D, et al. Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase. J Med Chem. 2014 Mar 27; 57(6):2582-8.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.