Biological Activity
CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27.
In Vitro
CID 1375606 is a GPR27-specific surrogate agonist. GPR27 is characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system. In addition, it has recently been linked to insulin secretion[1].
In Vivo
No in vivo data are provided in the current product source. Contact us for further information.
Target
GPR 27[1].
References & source
[1]. Dupuis N, et al. Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes β-Arrestin 2 Recruitment. Mol Pharmacol. 2017 Jun;91(6):595-608.
Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.
