DC Chemicals · Product datasheet

CID 1375606 — Datasheet

CAT. NO. DC12285

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ParameterValue
Chemical NameCID 1375606
CAS No.313493-80-0
SynonymsCID 1375606;CID-1375606;CID1375606
FormulaC20H14Cl2N2O2
M.Wt385.24
SMILESO=C(NC1=CC=C(C(NC2=CC=CC=C2)=O)C=C1)C3=CC=C(Cl)C=C3Cl
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27.

In Vitro

CID 1375606 is a GPR27-specific surrogate agonist. GPR27 is characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system. In addition, it has recently been linked to insulin secretion[1].

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

Target

GPR 27[1].

References & source

[1]. Dupuis N, et al. Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes β-Arrestin 2 Recruitment. Mol Pharmacol. 2017 Jun;91(6):595-608.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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