FIN56 chemical structure
Chemical structureResearch use onlyView full-size structure
CAT. NO. DC10522Featured

FIN56

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Product overview

Description & Application

FIN56 is a specific inducer of ferroptosis.

ParameterValue
Chemical NameFIN56
CAS No.1083162-61-1
FormulaC25H31N3O5S2
M.Wt517.67
SMILESO=S(=O)(NC1CCCCC1)c1ccc2c(c1)C(=NO)c1cc(S(=O)(=O)NC3CCCCC3)ccc1-2
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Chemical identity references

Biological Activity

FIN56 is a specific inducer of ferroptosis.

In Vitro

FIN56 causes the loss of GPX4 activity in cell lysates. FIN56-induced cell death is suppressed by GFP-GPX4 fusion protein overexpression. FIN56 triggers ferroptosis through a mechanism involving the regulation of GPX4 protein abundance[1].

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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