HBX41108

Biological Activity

Inhibitor of ubiquitin-specific protease (USP) 7 activity (IC50 = 424 nM). Displays uncompetitive inhibition. Also inhibits USP7-mediated p53 deubiquitination (IC50 = 0.8 μM). Stabilizes p53 and inhibits cancer cell growth; induces p53-dependent apoptosis in p53 wild type and null isogenic cancer cell lines. For the detailed information of HBX41108 , the solubility of HBX41108 in water, the solubility of HBX41108 in DMSO, the solubility of HBX41108 in PBS buffer, the animal experiment (test) of HBX41108 , the cell expriment (test) of HBX41108 , the in vivo, in vitro and clinical trial test of HBX41108 , the EC50, IC50,and affinity,of HBX41108 , For the detailed information of HBX41108 , the solubility of HBX41108 in water, the solubility of HBX41108 in DMSO, the solubility of HBX41108 in PBS buffer, the animal experiment (test) of HBX41108 , the cell expriment (test) of HBX41108 , the in vivo, in vitro and clinical trial test of HBX41108 , the EC50, IC50,and affinity,of HBX41108 , Please contact DC Chemicals.

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.