Chemical structureResearch use only

CAT. NO. DC7657Featured

WH-4-023

Name: WH-4-023
Brand: DC Chemicals
SKU: DC7657
Price: 450.0 USD

Pack Sizes & Prices

TotalUS$450

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Product overview

Description & Application

WH-4-023 is a potent and selective dual Lck/Src inhibitor with IC50 of 2 nM/6 nM for Lck and Src kinase respectively; little inhibition on p38α and KDR.

Parameter	Value
Chemical Name	Dual LCK/SRC inhibitor
CAS No.	837422-57-8
Synonyms	Dual LCK/SRC inhibitor
Formula	C32H36N6O4
M.Wt	568.67
SMILES	CC1=C(C(=CC=C1)C)OC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCN(CC5)C
Purity	>98%
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

WH-4-023 is a potent and selective dual Lck/Src inhibitor with IC50 of 2 nM/6 nM for Lck and Src kinase respectively; little inhibition on p38α and KDR.

In Vitro

WH-4-023 shows a similar potency increase on Lck as 2-substituted variants[1].

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

View online datasheet Request COA / MSDS

Refer to the certificate supplied with your lot for batch-specific release results.

Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Solution calculator

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