BRD-810 chemical structure
Chemical structureResearch use only
CAT. NO. DC60643Featured

BRD-810

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TotalUS$1,600
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Product overview

Description & Application

BRD-810 is a potent and selective MCL1 inhibitor with Kd of 0.3 nM (SPR) and IC50 of 0.4 nM (MCL1-Noxa HTRF), respectively. BRD-810 is a rapidly cleared inhibitor of MCL1 that has robust antitumor efficacy in hematological and solid tumor cancer models.

ParameterValue
Chemical NameBRD-810
CAS No.2329719-65-3
FormulaC39H44ClFN4O5
M.Wt703.24
SMILESCCC1=C2C(=NN1C)[C@@H](CCN1CCOCC1)OCCCCN1C(C(=O)O)=C(CCCOC3=CC=CC4=C3C=CC(F)=C4)C3=CC=C(Cl)C2=C31
Purity98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

BRD-810 is a potent and selective MCL1 inhibitor with Kd of 0.3 nM (SPR) and IC50 of 0.4 nM (MCL1-Noxa HTRF), respectively. BRD-810 is a rapidly cleared inhibitor of MCL1 that has robust antitumor efficacy in hematological and solid tumor cancer models.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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