BCAT-IN-2 chemical structure
Chemical structureResearch use only
CAT. NO. DC45788Featured

BCAT-IN-2

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Product overview

Description & Application

BCAT-IN-2 is a potent, selective and orally active inhibitor of mitochondrial branched-chain aminotransferase (BCATm), with a pIC50 of 7.3. BCAT-IN-2 shows selectivity for BCATm over BCATc (pIC50=6.6). BCAT-IN-2 can be used for the research of obesity and dislipidema.

ParameterValue
Chemical NameBCAT-IN-2
CAS No.1800024-45-6
SynonymsBDBM50118522;2-((4-Chloro-2,6-difluorobenzyl)amino)-7-oxo-5-propyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile;2-(2,6-Difluoro-4-chlorobenzylamino)-5-propyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile;BCAT-IN-2
FormulaC17H14ClF2N5O
M.Wt377.775768756866
SMILESClC1C=C(C(=C(C=1)F)CNC1=C(C#N)C2=NC(=CC(N2N1)=O)CCC)F
Purity98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

BCAT-IN-2 is a potent, selective and orally active inhibitor of mitochondrial branched-chain aminotransferase (BCATm), with a pIC50 of 7.3. BCAT-IN-2 shows selectivity for BCATm over BCATc (pIC50=6.6). BCAT-IN-2 can be used for the research of obesity and dislipidema.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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