NMDAR/TRPM4 inhibitor 8 chemical structure
Chemical structureResearch use only
CAT. NO. DC39201Featured

NMDAR/TRPM4 inhibitor 8

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TotalUS$800
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Product overview

Description & Application

NMDAR/TRPM4 inhibitor 8 (Compound 8) is a neuroprotective NMDAR-TRPM4 interaction interface inhibitor but spare the critical healthy NMDAR function.

ParameterValue
Chemical NameN*1*-(3-Bromo-benzyl)-N*1*-ethyl-ethane-1,2-diamine
CAS No.1353979-43-7
SynonymsN*1*-(3-bromo-benzyl)-n*1*-ethyl-ethane-1,2-diamine;N1-(3-bromobenzyl)-N1-ethylethane-1,2-diamine;AM94336;N-(3-Bromobenzyl)-N-ethyl-1,2-ethanediamine;NMDAR/TRPM4-IN-2 free base
FormulaC11H17BrN2
M.Wt257.17
SMILESBrC1=CC=CC(=C1)CN(CC)CCN
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

NMDAR/TRPM4 inhibitor 8 (Compound 8) is a neuroprotective NMDAR-TRPM4 interaction interface inhibitor but spare the critical healthy NMDAR function.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

Coupling of NMDA receptors and TRPM4 guides discovery of unconventional neuroprotectants.Jing Yan, Peter Bengtson, Science 09 Oct 2020

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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