Deudextromethorphan chemical structure
Chemical structureResearch use only
CAT. NO. DC26015Featured

Deudextromethorphan

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TotalUS$700
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Product overview

Description & Application

Deudextromethorphan (AVP-786) is a deuterated form of dextromethorphan/quinidine (AVP-923, Nuedexta). Deudextromethorphan, a glutamate-targeting agent, is an orally active N-methyl-D-aspartate (NMDA) receptor antagonist. Deudextromethorphan can be used for the research of Pseudo-Bulbar Affect, traumatic brain injury, behavioral disinhibition and agitation in AD[1][2][3].

ParameterValue
Chemical NameDeudextromethorphan
CAS No.1079043-55-2
SynonymsAvp-786;(9alpha,13alpha,14alpha)-3-(Methoxy-d3)-17-(methyl-d3)morphinan;Deudextromethorphan;d6-DM;427476LZFT;D6-Dextromethorphan;Deudextromethorphan [USAN];Deudextromethorphan (USAN/INN);D11152;C100003;Q27258502
FormulaC18H25NO
M.Wt277.440
SMILESO(C([2H])([2H])[2H])C1C=CC2C[C@H]3[C@H]4CCCC[C@]4(C=2C=1)CCN3C([2H])([2H])[2H]
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Deudextromethorphan (AVP-786) is a deuterated form of dextromethorphan/quinidine (AVP-923, Nuedexta). Deudextromethorphan, a glutamate-targeting agent, is an orally active N-methyl-D-aspartate (NMDA) receptor antagonist. Deudextromethorphan can be used for the research of Pseudo-Bulbar Affect, traumatic brain injury, behavioral disinhibition and agitation in AD[1][2][3].

In Vitro

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In Vivo

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References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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