For research use only. We do not sell to patients.
Small molecule tools for RNA delivery / AZD-7648
AZD-7648 chemical structure
CAT. NO. DC20278Featured

AZD-7648

Pack size & price

USD
TotalUS$550
Ships from ShanghaiFor research use only
Product overview

Description & Application

AZD-7648 is a potent and selective DNA-PK inhibitor. AZD7648,enhances HDR efficiency in CRISPR-Cas9 gene editing by shifting DNA repair from the error-prone NHEJ pathway to the precise HDR pathway, significantly improving gene targeting outcomes in human cells for effective ex vivo gene therapies.

CAS No.2230820-11-6
Chemical Name7-Methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one
SynonymsAZD7648;AZD-7648;97A09L5JCK;7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one;7-Methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7H-purin-8(9H)-one;7-methyl-2-[(7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(oxan-4-yl)purin-8-one;GTPL10601;US10407446, Example 3;BDBM413450;BCP30676;AZD 7648;AZD7648;N
SMILESO1C([H])([H])C([H])([H])C([H])(C([H])([H])C1([H])[H])N1C(N(C([H])([H])[H])C2=C([H])N=C(N([H])C3=C([H])N4C(C([H])=C3C([H])([H])[H])=NC([H])=N4)N=C12)=O
FormulaC18H20N8O2
M.Wt380.4038
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Shipping conditionShips from Shanghai; packaging confirmed at order.
PublicationNot available
Product classificationSmall molecule tools for RNA delivery
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
Enter any three values to calculate the fourth.
C₁V₁ = C₂V₂
Enter any three values to calculate the fourth.
Preparing stock solutions

Quick preparation table

Solvent volumes update from the molecular weight above.

Mass1 mM5 mM10 mM
10 mg26.2879 mL5.2576 mL2.6288 mL
25 mg65.7196 mL13.1439 mL6.5720 mL
50 mg131.4393 mL26.2879 mL13.1439 mL
100 mg262.8786 mL52.5757 mL26.2879 mL
250 mg657.1964 mL131.4393 mL65.7196 mL

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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
Ships from Shanghai. Storage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.