For research use only. We do not sell to patients.
Small molecule tools for RNA delivery / SCH58261
SCH58261 chemical structure
CAT. NO. DC9284Featured

SCH58261

Pack size & price

USD
TotalUS$500
Ships from ShanghaiFor research use only
Product overview

Description & Application

SCH 58261 is a potent and selective A2a adenosine receptor antagonist with Ki of 2.3 nM and 2 nM for rat A2a and bovine A2a. SCH58261 could enhance the transfection efficiency to 2-fold to 5-fold of Lipofectamine 3000 and LNP, all of which are currently approved for clinical use in the treatment of the most common malignant tumors.

CAS No.160098-96-4
Chemical NameSCH-58261,SCH 58261
SynonymsSCH-58261,SCH 58261
SMILESC1=CC=C(C=C1)CCN2C3=C(C=N2)C4=NC(=NN4C(=N3)N)C5=CC=CO5
FormulaC18H15N7O
M.Wt345.36
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Shipping conditionShips from Shanghai; packaging confirmed at order.
PublicationImproving lipid nanoparticles delivery efficiency of macrophage cells by using immunomodulatory small molecules-Lirong Yi PhD , Ziyan Zhang MSc-Nanomedicine: Nanotechnology, Biology and Medicine Volume 64, February 2025, 102809
Product classificationSmall molecule tools for RNA delivery
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
Enter any three values to calculate the fourth.
C₁V₁ = C₂V₂
Enter any three values to calculate the fourth.
Preparing stock solutions

Quick preparation table

Solvent volumes update from the molecular weight above.

Mass1 mM5 mM10 mM
10 mg28.9553 mL5.7911 mL2.8955 mL
25 mg72.3882 mL14.4776 mL7.2388 mL
50 mg144.7765 mL28.9553 mL14.4776 mL
100 mg289.5529 mL57.9106 mL28.9553 mL
250 mg723.8823 mL144.7765 mL72.3882 mL

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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
Ships from Shanghai. Storage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.