For research use only. We do not sell to patients.
Small molecule tools for RNA delivery / Bropirimine
Bropirimine chemical structure
CAT. NO. DC36761Featured

Bropirimine

Pack size & price

USD
TotalUS$250
Ships from ShanghaiFor research use only
Product overview

Description & Application

Bropirimine is a synthetic agonist for toll-like receptor 7 (TLR7). Bropirimine inhibits differentiation of osteoclast precursor cells into osteoclasts via TLR7-mediated production of IFN-β. Bropirimine is an orally active immunomodulator that has demonstrated anticancer activity in transitional cell carcinoma in situ (CIS) in both the bladder and upper urinary Bropirimine could enhance the transfection efficiency to 2-fold to 5-fold of Lipofectamine 3000 and LNP, all of which are currently approved for clinical use in the treatment of the most common malignant tumors.

CAS No.56741-95-8
Chemical Name4(1H)-Pyrimidinone, 2-amino-5-bromo-6-phenyl-
SynonymsBropirimine
SMILESO=C1NC(N)=NC(C2=CC=CC=C2)=C1Br
FormulaC10H8BrN3O
M.Wt266.09
Purity>98%
StorageNot available
Shipping conditionShips from Shanghai; packaging confirmed at order.
PublicationImproving lipid nanoparticles delivery efficiency of macrophage cells by using immunomodulatory small molecules-Lirong Yi PhD , Ziyan Zhang MSc-Nanomedicine: Nanotechnology, Biology and Medicine Volume 64, February 2025, 102809
Product classificationSmall molecule tools for RNA delivery
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
Enter any three values to calculate the fourth.
C₁V₁ = C₂V₂
Enter any three values to calculate the fourth.
Preparing stock solutions

Quick preparation table

Solvent volumes update from the molecular weight above.

Mass1 mM5 mM10 mM
10 mg37.5813 mL7.5163 mL3.7581 mL
25 mg93.9532 mL18.7906 mL9.3953 mL
50 mg187.9063 mL37.5813 mL18.7906 mL
100 mg375.8127 mL75.1625 mL37.5813 mL
250 mg939.5317 mL187.9063 mL93.9532 mL

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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
Ships from Shanghai. Storage: Please contact us for handling guidance.
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.