GOT1 inhibitor 2c chemical structure
Chemical structureResearch use only
CAT. NO. DC12542Featured

GOT1 inhibitor 2c

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TotalUS$1,950
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Product overview

Description & Application

GOT1 inhibitor 2c is a first-in-class, non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with IC50 of 8.2 uM.

ParameterValue
Chemical NameN-(4-chlorophenyl)-4-(1H-indol-4-yl)piperazine-1-carboxamide
CAS No.732973-87-4
FormulaC19H19ClN4O
M.Wt354.83
SMILESO=C(N1CCN(C2=CC=CC3=C2C=CN3)CC1)NC4=CC=C(Cl)C=C4
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

GOT1 inhibitor 2c is a first-in-class, non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with IC50 of 8.2 uM.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

1. Anglin J, et al. Bioorg Med Chem Lett. 2018 Sep 1;28(16):2675-2678.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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