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Small molecule tools for RNA delivery / NAV-2729（Grassofermata）
NAV-2729（Grassofermata） chemical structure
CAT. NO. DC11971Featured

NAV-2729（Grassofermata）

Pack size & price

USD
TotalUS$350
Ships from ShanghaiFor research use only
Product overview

Description & Application

NAV 2729 (NAV2729) is a chemical potentiator for mRNA-LNPs, increasing the delivery efficiencies of mRNA-LNPs in vitro and in vivo.

CAS No.419547-11-8
Chemical Name2-benzyl-3-(4-chlorophenyl)-5-(4-nitrophenyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
SynonymsNAV-2729;NAV2729
SMILESC12=C(C3=CC=C(Cl)C=C3)C(CC3=CC=CC=C3)=NN1C(=O)C=C(C1=CC=C([N+]([O-])=O)C=C1)N2
FormulaC25H17ClN4O3
M.Wt456.88
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Shipping conditionShips from Shanghai; packaging confirmed at order.
Publication1. Yoo JH, et al. Cancer Cell. 2016 Jun 13;29(6):889-904. 2. Benabdi S, et al. Biochemistry. 2017 Sep 26;56(38):5125-5133.
Product classificationSmall molecule tools for RNA delivery
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
Enter any three values to calculate the fourth.
C₁V₁ = C₂V₂
Enter any three values to calculate the fourth.
Preparing stock solutions

Quick preparation table

Solvent volumes update from the molecular weight above.

Mass1 mM5 mM10 mM
10 mg21.8876 mL4.3775 mL2.1888 mL
25 mg54.7190 mL10.9438 mL5.4719 mL
50 mg109.4379 mL21.8876 mL10.9438 mL
100 mg218.8759 mL43.7752 mL21.8876 mL
250 mg547.1896 mL109.4379 mL54.7190 mL

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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
Ships from Shanghai. Storage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.