Solriamfetol hydrochloride chemical structure
Chemical structureResearch use only
CAT. NO. DC11529Featured

Solriamfetol hydrochloride

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TotalUS$650
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Product overview

Description & Application

Solriamfetol (JZP-110) is a selective dopamine and norepinephrine reuptake inhibitor with robust wake-promoting effects. Solriamfetol binds to dopamine and norepinephrine transporters, so it can inhibit reuptake of dopamine and norepinephrine. Solriamfetol treatment significantly improves the ability to stay awake and subjective symptoms of excessive sleepiness in adults with narcolepsy.

ParameterValue
Chemical NameJZP-110 hydrochloride
CAS No.178429-65-7
SynonymsSolriamfetol hydrochloride;Solriamfetol (hydrochloride);K7RO88SP7A;Solriamfetol hydrochloride [USAN];Solriamfetol hydrochloride (USAN);Sunosi (TN);KAOVAAHCFNYXNJ-SBSPUUFOSA-N;SB19103;O-Carbamoyl-(D)-phenylalaninol hydrochloride;D11328;(betaR)-beta-amino-Benzenepropanol 1-carbamate hydrochloride (1:1);JZP-110 hydrochloride
FormulaC10H15ClN2O2
M.Wt230.6913
SMILESCl[H].O(C(N([H])[H])=O)C([H])([H])[C@@]([H])(C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H])N([H])[H]
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Solriamfetol (JZP-110) is a selective dopamine and norepinephrine reuptake inhibitor with robust wake-promoting effects. Solriamfetol binds to dopamine and norepinephrine transporters, so it can inhibit reuptake of dopamine and norepinephrine. Solriamfetol treatment significantly improves the ability to stay awake and subjective symptoms of excessive sleepiness in adults with narcolepsy.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

[1]. Yang J, et al. Solriamfetol for the treatment of excessive daytime sleepiness associated with narcolepsy. Expert Rev Clin Pharmacol. 2019 Aug;12(8):723-728.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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