DC Chemicals · Product datasheet

Sabutoclax — Datasheet

CAT. NO. DC8444

Product page and current package options

ParameterValue
Chemical Name[2,2'-Binaphthalene]-5,5'-dicarboxamide, 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-N5,N5'-bis[(2R)-2-phenylpropyl]-, (1R)
CAS No.1228108-65-3
FormulaC42H40N2O8
M.Wt700.78
SMILESC(O)1=C2C(C(C(NC[C@@H](C3=CC=CC=C3)C)=O)=C(O)C(O)=C2)=CC(C)=C1C1=C(C)C=C2C(=C1O)C=C(O)C(O)=C2C(NC[C@@H](C1=CC=CC=C1)C)=O
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Sabutoclax is a potent and effective Bcl-2 Family (Bcl-2, Bcl-XL, Mcl-1, Bfl-1) inhibitor with IC50s of 0.32 μM, 0.31 μM, 0.20 μM, and 0.62 μM, respectively.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Cart

Request quotation