Biological Activity
Israpafant (Y24180) is a specific antagonist of PAF receptor that inhibits PAF-induced rabbit platelet aggregation in vitro (IC50=3.84 nM), with little effect on adenosine diphosphate- or arachidonic acid-induced aggregation.
In Vitro
No in vitro data are provided in the current product source. Contact us for further information.
In Vivo
No in vivo data are provided in the current product source. Contact us for further information.
References & source
1. Takehara S, et al. Prostaglandins. 1990 Dec;40(6):571-83.
2. Kagoshima M, et al. Pharmacology. 1997 May;54(5):261-70.
3. Yamaguchi S, et al. Inflamm Res. 2000 Nov;49(11):584-90.
Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.