PSMA-617 Linker chemical structure
Chemical structureResearch use only
CAT. NO. DC33611Featured

PSMA-617 Linker

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Product overview

Description & Application

Vipivotide tetraxetan Ligand-Linker Conjugate (PSMA-617 Ligand-Linker Conjugate) is composed of a linker and Glutamate-urea-Lysine, can be used to synthesize Vipivotide tetraxetan (PSMA-617). Glutamate-urea-Lysine is is the selective pharmacophore to bind to prostate specific membrane antigen (PSMA).

ParameterValue
Chemical NameVipivotide tetraxetan Ligand-Linker Conjugate
CAS No.1703768-74-4
SynonymsPSMA-617 Linker;Vipivotide tetraxetan Linker;JUN68744;(((S)-5-((S)-2-((1r,4S)-4-(aminomethyl)cyclohexane-1-carboxamido)-3-(naphthalen-2-yl)propanamido)-1-carboxypentyl)carbamoyl)-L-glutamic acid;Vipivotide tetraxetan Ligand-Linker Conjugate
FormulaC33H45N5O9
M.Wt655.738508939743
SMILESO=C(C1CCC(CN)CC1)N[C@H](C(NCCCC[C@@H](C(=O)O)NC(N[C@H](C(=O)O)CCC(=O)O)=O)=O)CC1C=CC2C=CC=CC=2C=1
Purity>98%
Storage-20

Biological Activity

Vipivotide tetraxetan Ligand-Linker Conjugate (PSMA-617 Ligand-Linker Conjugate) is composed of a linker and Glutamate-urea-Lysine, can be used to synthesize Vipivotide tetraxetan (PSMA-617). Glutamate-urea-Lysine is is the selective pharmacophore to bind to prostate specific membrane antigen (PSMA).

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

[1]. Benešová M, et al. Albumin-Binding PSMA Ligands: Optimization of the Tissue Distribution Profile. Mol Pharm. 2018 Mar 5;15(3):934-946.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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