Biological Activity
MQAE is a fluorescent indicator that is quenched via collision with chloride, and is more sensitive and selective than 36Cl and microelectrode-based methods for chloride measurement in cells.
In Vitro
Bath-applied to acute brain slices, MQAE provides high-quality labeling of neuronal cells and their processes[1]. MQAE fluorescence is adequate and comparable method for measuring cAMP-dependent chloride transport in individual cells[2]. MQAE can be used to measure intracellular chloride concentration in primary cultures of rat aortic smooth muscle cells (VSMC)[3].
In Vivo
No in vivo data are provided in the current product source. Contact us for further information.
References & source
Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.