DC Chemicals · Product datasheet

WNK463 — Datasheet

CAT. NO. DC9883

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ParameterValue
Chemical NameWNK 463,WNK-463
CAS No.2012607-27-9
SynonymsWNK 463,WNK-463
FormulaC21H24F3N7O2
M.Wt463.46
SMILESCC(C)(C)NC(=O)C1=CN=CN1C2CCN(CC2)C3=NC=C(C=C3)C4=NN=C(O4)C(F)(F)F
Purity>98%

Biological Activity

WNK463 is an orally bioavailable pan-WNK-kinase inhibitor with IC50s of 5, 1, 6, and 9 nM for WNK1, WNK 2, WNK 3, and WNK 4, respectively.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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