DC Chemicals · Product datasheet

Cytochalasin H — Datasheet

CAT. NO. DC9835

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ParameterValue
Chemical Name1H-Cycloundec[d]isoindol-1-one,15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-,(3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-
CAS No.53760-19-3
Synonyms1H-Cycloundec[d]isoindol-1-one,15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-,(3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-;Cytochalasin H from Phomopsis sp;1H-Cycloundec[d]isoindol-1-one,15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-d...;1H-Cycloundec[d]isoindol-1-one,15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-me;CYTOCHALASIN H;<11>Cytochalasin;19-triene-1-one;cytochalasin U;cytochalasinhfromphomopsissp.;kodocytochalasin-1;paspalin;Paspalin P1;paspalinpi;Cytochalasin O;Kodocytochalasin 1
FormulaC30H39NO5
M.Wt493.63436
SMILESC[C@H]1CC=CC2[C@@]3(C(=O)N[C@@H](CC4C=CC=CC=4)C3C(C([C@H]2O)=C)C)[C@H](OC(=O)C)C=C[C@](C)(O)C1 |c:13,15,33,t:3,17,&1:1,6,10,21,25,32|
Purity>95%
Storage4°C for 1 year, -20°C for more than 2 years

Biological Activity

Cytochalasin H is a potent inhibitor of actin incorporation into filaments,a cell-permeable fungal toxin used in actin polymerization studies and cytological research. Cytochalasin H suppresses the production of reactive oxygen species by stimulated human neutrophils, blocks endocytosis of CD59 in lymphocytes, and shows anti-angiogenic activity both in vitro and in vivo.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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