DC Chemicals · Product datasheet

DB07268 — Datasheet

CAT. NO. DC8826

Product page and current package options

ParameterValue
Chemical NameBenzamide, 2-[[2-[(3-hydroxyphenyl)amino]-4-pyrimidinyl]amino]-
CAS No.929007-72-7
SynonymsBenzamide, 2-[[2-[(3-hydroxyphenyl)amino]-4-pyrimidinyl]amino]-;DB07268;DB-07268
FormulaC17H15N5O2
M.Wt321.333302736282
SMILESO=C(N)C1=CC=CC=C1NC2=NC(NC3=CC=CC(O)=C3)=NC=C2
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.

In Vitro

DB07268 (Compound 2b) also inhibits CHK1, PAK4, AKT1, and ERK2 with IC50s of 0.82 μM, 5.5 μM, 15 μM, and 25 μM, respectively[1].

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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