DC Chemicals · Product datasheet

APD597(JNJ-38431055) — Datasheet

CAT. NO. DC8804

Product page and current package options

ParameterValue
Chemical NameAPD597
CAS No.897732-93-3
Synonymspropan-2-yl 4-[5-methoxy-6-[(2-methyl-6-methylsulfonylpyridin-3-yl)amino]pyrimidin-4-yl]oxypiperidine-1-carboxylate;APD 597;APD-597;APD597;JNJ-38431055;APD597 (JNJ-38431055);4-[[6-[(6-Methylsulfonyl-2-methylpyridin-3-yl)amino]-5-methoxypyrimidin-4-yl]oxy]piperidine-1-carboxylic acid isopropyl ester; APD-597; APD 597; JNJ38431055; JNJ 38431055;CS-1557;1-Piperidinecarboxylic acid, 4-[[5-methoxy-6-[[2-methyl-6-(methylsulfonyl)-3-pyridinyl]amino]-4-pyrimidinyl]oxy]-, 1-methylethyl ester;4-[6-(6-methanesulfonyl-2-methyl-pyridin-3-ylamino)-5-methoxy-pyrimidin-4-yloxy]-piperidine-1-carboxylic acid isopropyl ester;BS-17790;EX-A1213;897732-93-3;propan-2-yl 4-({6-[(6-methanesulfonyl-2-methylpyridin-3-yl)amino]-5-methoxypyrimidin-4-yl}oxy)piperidine-1-carboxylate;ADP-597;345354O7AT;WPDCHTSXOPUOII-UHFFFAOYSA-N;isopropyl 4-(5-methoxy-6-(2-methyl-6-(methylsulfonyl)pyridin-3-ylamino)pyrimidin-4-yloxy)piperidine-1-carboxylate;DB-109001;UNII-345354O7AT;Q27893071;ISOPROPYL 4-({6-[(6-METHANESULFONYL-2-METHYLPYRIDIN-3-YL)AMINO]-5-METHOXYPYRIMIDIN-4-YL}OXY)PIPERIDINE-1-CARBOXYLATE;SB16860;BRD-K86226872-001-01-6;BCP17733;APD597(JNJ-38431055);DTXSID10237885;JNJ 38431055;SCHEMBL386884;HY-15566;isopropyl 4-((5-methoxy-6-((2-methyl-6-(methylsulfonyl)pyridin-3-yl)amino)pyrimidin-4-yl)oxy)piperidine-1-carboxylate;C77029;DB12084;JNJ38431055;CHEMBL1951032;AC-33177;BDBM50364559;NS00072236;AKOS026751481;4-((6-((6-METHYLSULFONYL-2-METHYLPYRIDIN-3-YL)AMINO)-5-METHOXYPYRIMIDIN-4-YL)OXY)PIPERIDINE-1-CARBOXYLIC ACID ISOPROPYL ESTER;GTPL5727;CS-5278
FormulaC21H29N5O6S
M.Wt479.549863576889
SMILESO=C(N1CCC(OC2C(OC)=C(NC3C(C)=NC(S(C)(=O)=O)=CC=3)N=CN=2)CC1)OC(C)C
Purity98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

APD597 is a GPR119 agonist intended for the treatment of type 2 diabetes, with EC50 of 46 nM for hGPR119.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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