DC Chemicals · Product datasheet

Cambendazol — Datasheet

CAT. NO. DC8730

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ParameterValue
Chemical NameCarbamic acid,N-[2-(4-thiazolyl)-1H-benzimidazol-6-yl]-, 1-methylethyl ester
CAS No.26097-80-3
SynonymsCarbamic acid,N-[2-(4-thiazolyl)-1H-benzimidazol-6-yl]-, 1-methylethyl ester;Cambendazole;isopropyl 2-(thiazol-4-yl)-3H-benzo[d]imidazol-5-ylcarbamate;propan-2-yl N-[2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-yl]carbamate;(2-thiazol-4-yl-1(3)H-benzoimidazol-5-yl)-carbamic acid isopropyl ester;[2-(4-thiazolyl)-1H-benzimidazol-5-yl]carbamic acid 1-methylethyl ester;5-isopropoxycarbonylamino-2-(4'-thiazolyl)-benzimidazole;Bonlam;Cambenzole;Camdan;Camvet;CBDZ;Equiben;Isopropyl 2-(4-thiazolyl)-5-benzimidazolecarbamate;NOE [French];Novazole;Noviben;2-(4-Thiazolyl)-5-isopropoxycarbonylaminobenzimidazole;MK 905;NSC 377071
FormulaC14H14N4O2S
M.Wt302.352
SMILESCC(C)OC(NC1=CC2N=C(C3N=CSC=3)NC=2C=C1)=O
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Cambendazol is an antihelmintic that, at a dose of 50 mg/kg/day in mice, eradicates S. ratti adult worms from intestine and S. stercoralis larva from muscle.It inhibits polymerization of microtubules isolated from bovine brain with an IC50 value of 64.2 µM.Formulations containing cambendazol have been used to treat strongyloidiasis in humans and have been studied as potential chemotherapeutics.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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