DC Chemicals · Product datasheet

S-(5'-Adenosyl)-L-methionine chloride(SAM) — Datasheet

CAT. NO. DC8616

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ParameterValue
Chemical NameS-(5'-Adenosyl)-L-methionine chloride (hydrochloride)
CAS No.86867-01-8
SynonymsS-(5'-Adenosyl)-L-methionine chloride (hydrochloride);S-(5′-Adenosyl)-L-methionine chloride dihydrochloride;S-(5-Adenosyl)-L-methionine chloride dihydrochloride
FormulaC15N6O5Scl3H25
M.Wt507.8202
SMILESC[S+](CC[C@@H](C(=O)[O-])N)C[C@@H]1C([C@@H]([C@H](N2C=NC3=C(N)N=CN=C32)O1)O)O.Cl.Cl.Cl
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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