DC Chemicals · Product datasheet

8-Bromo-cAMP — Datasheet

CAT. NO. DC8388

Product page and current package options

ParameterValue
Chemical Name8-Bromo-cAMP
CAS No.76939-46-3
SynonymsAdenosine, 8-bromo-,cyclic 3',5'-(hydrogen phosphate), monosodium salt (9CI);8-BR-CAMP NA;8-BroMoadenosine 3',5'-cyclic Monophosphate sodiuM salt;8-Bromo-cAMP, sodium salt;8-Bromo-cAMP, sodium salt,8-Bromoadenosine-3',5'-cyclicmonophosphatesodiumsalt;8-bromo-Cyclic AMP (sodium salt);8-BR-CAMP SODIUM SALT;8-BROM-ADENOSIN-3',5'-CYCLOPHOSPHAT;8-Bromoadenosine 3',5'-phosphoric acid sodium salt;8-bromoadenosine 3:5-cyclic*monophosphate sodiu;8-BROMOADENOSINE 3':5'-CYCLICMONOPHOSPHA TE SODIUM;8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT;8-BROMOADENOSINE-3',5'-CYCLOPHOSPHATE SODIUM SALT;8-BROMO-CAMP,NA;CAMP,8-BR,NA;8-Br-cAMP;4H-Furo[3,2-d]-1,3,2-dioxaphosphorin,adenosine deriv.;8-Bromo-cAMP sodium salt;1PVH7X89H4;8-bromo-cAMP;MLS002153216;SMR000326869;8-Bromo-cAMP(sodium salt);MLS000860010;8-Bromo cyclic AMP sodium salt;AOB5956;HMS2233B10;HMS3412M07;B9000;8-Bromo-adenosine 3',5'-cyclic-monophosphate, sodi
FormulaC10H10BrN5NaO6P
M.Wt430.0838
SMILESBrC1=NC2=C(N([H])[H])N=C([H])N=C2N1[C@@]1([H])[C@@]([H])([C@@]2([H])[C@@]([H])(C([H])([H])OP(=O)([O-])O2)O1)O[H].[Na+]
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt), a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA)[1].

In Vitro

8-Bromo-cAMP sodium salt is a brominated derivative of cyclic AMP. 8-Bromo-cAMP sodium salt enhances the efficiency of cellular reprogramming. 8-Bromo-cAMP sodium salt improves the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells. 8-Bromo-cAMP sodium salt inhibits proliferation, induce differentiation and apoptosis in a malignant glioma cell line (A-172) and an esophageal cancer cell line (Eca-109)[1].

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Cart

Request quotation