DC Chemicals · Product datasheet

Droxinostat — Datasheet

CAT. NO. DC8350

Product page and current package options

ParameterValue
Chemical Name4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide
CAS No.99873-43-5
SynonymsDroxinostat;4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide;Droxinostat ( NS41080);NS 41080;NS-41080;MLS000109046;SMR000104993;XCH;NS41080;CBMicro_030914;CBChromo1_000102;MLS006011918;GTPL8464;cid_568416;Droxinostat, >=98% (HPLC);BDBM53719;JHSXDAWGLCZYSM-UHFFFAOYSA-N;HMS3260P20;HMS3654J06;BCPP000249;HMS2177P11;BCP23435;Tox21_500319;STK945834;s1422;BCP9000629;NCGC00087387-
FormulaC11H14ClNO3
M.Wt243.6868
SMILESClC1C([H])=C([H])C(=C(C([H])([H])[H])C=1[H])OC([H])([H])C([H])([H])C([H])([H])C(N([H])O[H])=O
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Selective HDAC3, HDAC6 and HDAC8 inhibitor (IC50 values are 16.9, 2.47 and 1.46 μM for HDAC3, 6 and 8 respectively). Induces apoptosis. Shows antitumor effects in vivo. For the detailed information of Droxinostat, the solubility of Droxinostat in water, the solubility of Droxinostat in DMSO, the solubility of Droxinostat in PBS buffer, the animal experiment (test) of Droxinostat, the cell expriment (test) of Droxinostat, the in vivo, in vitro and clinical trial test of Droxinostat, the EC50, IC50,and affinity,of Droxinostat, For the detailed information of Droxinostat, the solubility of Droxinostat in water, the solubility of Droxinostat in DMSO, the solubility of Droxinostat in PBS buffer, the animal experiment (test) of Droxinostat, the cell expriment (test) of Droxinostat, the in vivo, in vitro and clinical trial test of Droxinostat, the EC50, IC50,and affinity,of Droxinostat, Please contact DC Chemicals.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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