DC Chemicals · Product datasheet

Etelcalcetide Hydrochloride(AMG-416) — Datasheet

CAT. NO. DC8189

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Parameter	Value
Chemical Name	Etelcalcetide Hydrochloride(AMG-416)
CAS No.	1334237-71-6
Formula	C38H73N21O10S2
M.Wt	1048.27
Parent-moiety SMILES	CC(=O)N[C@H](CSSC[C@H](N)C(=O)O)C(=O)N[C@H](C)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](C)C(=O)N[C@H](CCCNC(=N)N)C(N)=O
Purity	>98%
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Structure and molecular-weight basis	Parent compound values; hydrochloride stoichiometry is unspecified (xHCl). The SMILES depicts the parent moiety.
Material form	hydrochloride (xHCl)

Chemical identity references

Biological Activity

Etelcalcetide hydrochloride (AMG 416 hydrochloride) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis[1].

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.