DC Chemicals · Product datasheet

GMX1778(CHS-828) — Datasheet

CAT. NO. DC8139

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ParameterValue
Chemical NameCHS-828
CAS No.200484-11-3
SynonymsCHS 828;CHS-828;GMX1778;GMX-1778;N-Cyano-N'-(4-nitrophenyl)thiourea;N-cyano-N'-(6-(p-chlorophenoxy)hexyl)-N"-(4-pyridyl)guanidine;Thiourea,N-cyano-N'-(4-nitrophenyl);N-[6-(4-Chlorophenoxy)hexyl]-N′-cyano-N′′-4-pyridinyl-guanidine;GMX 1778;CHS828;GMX1778 (CHS828);8LAP87DNSZ;2-[6-(4-chlorophenoxy)hexyl]-1-cyano-3-pyridin-4-ylguanidine;Guanidine, N-[6-(4-chlorophenoxy)hexyl]-N'-cyano-N''-4-pyridinyl-;N-Cyano-N'-(6-(p-chlorophenoxy)hexyl)-N'-(4-pyridyl)guanidine;Guanidine, N-(6-(4-chlorophenoxy)hexyl)-N'-cyano-N''-4-pyridinyl-;BDBM81396
FormulaC19H22ClN5O
M.Wt371.86
SMILESClC1C([H])=C([H])C(=C([H])C=1[H])OC([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/N=C(\N([H])C#N)/N([H])C1C([H])=C([H])N=C([H])C=1[H]
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

GMX1778(CHS-828) is a potent inhibitor of NAD+ biosynthesis enzyme NAMPT with IC50 <25 nM.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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