Biological Activity
Talampanel is a potent and selective AMPA-receptor antagonist, is a potential new antiepileptic drug (AED).
In Vitro
Talampanel is a glutamate receptor inhibitor with anti-seizure activity.
In Vivo
Talampanel reduces motoneuronal calcium in a mouse model of ALS, but its effi cacy declines as the disease progresses, suggesting that medication initiation in the earlier stages of the disease might be more effective. [2]
References & source
Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.