DC Chemicals · Product datasheet

A-366 — Datasheet

CAT. NO. DC7855

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ParameterValue
Chemical NameCID 76285486
CAS No.1527503-11-2
SynonymsA 366;A-366;5′-Methoxy-6′-[3-(1-pyrrolidinyl)propoxy]-spiro[cyclobutane-1,3′-[3H]indol]-2′-amine;5'-Methoxy-6'-[3-(1-pyrrolidinyl)propoxy]spiro[cyclobutane-1,3'-[3H]indol]-2'-amine;5'-methoxy-6'-[3-(pyrrolidin-1-yl)propoxy]spiro[cyclobutane-1,3'-indole]-2'-amine;5'-methoxy-6'-(3-(pyrrolidin-1-yl)propoxy)spiro[cyclobutane-1,3'-indol]-2'-amine;5'-Methoxy-6'-[3-(Pyrrolidin-1-Yl)propoxy]spiro[cyclobutane-1,3'-Indol]-2'-Amine;A366;GTPL8238;BKCDJTRMYWSXMC-UHFFFAOYSA-N;BCP17827;BDBM50446376;s7572;SB1;CID 76285486
FormulaC19H27N3O2
M.Wt329.4366
SMILESO(C([H])([H])C([H])([H])C([H])([H])N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H])C1=C(C([H])=C2C(=C1[H])N=C(C12C([H])([H])C([H])([H])C1([H])[H])N([H])[H])OC([H])([H])[H]
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

A-366 is a potent histone methyltransferase G9a inhibitor with an IC50 of 3.3 nM.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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