DC Chemicals · Product datasheet

Fexinidazole — Datasheet

CAT. NO. DC7811

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ParameterValue
Chemical NameFexinidazole
CAS No.59729-37-2
Synonyms1-Methyl-2-((4-(methylthio)phenoxy)methyl)-5-nitro-1H-imidazole;Fexinidazole;1H-Imidazole,1-methyl-2-[[4-(methylthio)phenoxy]methyl]-5-nitro-;1-Methyl-2-((4-(methylthio)phenoxy)-methyl)-5-nitro-1H-imidazole;1-methyl-2-[(4-methylsulfanylphenoxy)methyl]-5-nitroimidazole;1-methyl-2-(4-methylsulfanyl-phenoxymethyl)-5-nitro-1H-imidazole;1-methyl-2-(4-methylthiophenyl-oxymethyl)-5-nitro-imidazole;AC1L2AGG;Fexinidazol;Fexinidazol [INN-Spanish];Fexinidazole [INN];Fexinidazolum;Fexinidazolum [INN-Latin];HOE 239;HOE-239;1-Methyl-2-[[4-(methylthio)phenoxy]methyl]-5-nitro-1H-imidazole;306ERL82IR;Fexinidazole (INN);AK116408;fexinidazole[inn];MLS006010234;M
FormulaC12H13N3O3S
M.Wt279.3149
SMILESO=[N+](C1=CN=C(COC2=CC=C(SC)C=C2)N1C)[O-]
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Fexinidazole is an antiparasitic agent. It has activity against Trypanosoma cruzi, Tritrichomonas foetus, Trichomonas vaginalis, Entamoeba histolytica, Trypanosoma brucei, and Leishmania donovani. The biologically relevant active metabolites in vivo are the sulfoxide and sulfone.. For the detailed information of Fexinidazole (HOE-239), the solubility of Fexinidazole (HOE-239) in water, the solubility of Fexinidazole (HOE-239) in DMSO, the solubility of Fexinidazole (HOE-239) in PBS buffer, the animal experiment (test) of Fexinidazole (HOE-239), the cell expriment (test) of Fexinidazole (HOE-239), the in vivo, in vitro and clinical trial test of Fexinidazole (HOE-239), the EC50, IC50,and affinity,of Fexinidazole (HOE-239), Please contact DC Chemicals.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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