Biological Activity
VX-661 is a second F508del CFTR corrector and help CFTR protein reach the cell surface.
In Vitro
In vitro, a combination of VX-661 and ivacaftor results in greater CFTR activity compared with VX-661 alone[2].
In Vivo
No in vivo data are provided in the current product source. Contact us for further information.
References & source
Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.