DC Chemicals · Product datasheet

Z271-0326 — Datasheet

CAT. NO. DC74459

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ParameterValue
Chemical NameZ271-0326
CAS No.1243002-72-3
SynonymsZ271 0326
FormulaC25H31N5O4S
M.Wt497.61
SMILESCCN(CC)C(=O)C1=C2C=C(C3CCN(S(=O)(=O)C4=CC=C(NC(C)=O)C=C4)CC3)C=CN2N=C1
Purity98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Z271-0326 is a first-in-class, potent and specifc inhibitor of NACK (Notch activation complex kinase) with SPR KD value of 0.89 uM, directly blocks NACK recruitment to the Notch ternary complex (NTC).

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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