DC Chemicals · Product datasheet

AD-5591 — Datasheet

CAT. NO. DC73704

Product page and current package options

ParameterValue
Chemical NameBenzamide, N-[(3-fluoro-4-methoxyphenyl)methyl]-5-[3-(hydroxymethyl)-2-pyridinyl]-2-(2-methylpropoxy)-
CAS No.1804942-45-7
SynonymsBenzamide, N-[(3-fluoro-4-methoxyphenyl)methyl]-5-[3-(hydroxymethyl)-2-pyridinyl]-2-(2-methylpropoxy)-
FormulaC25H27FN2O4
M.Wt438.491290330887
SMILESC(NCC1=CC=C(OC)C(F)=C1)(=O)C1=CC(C2=NC=CC=C2CO)=CC=C1OCC(C)C
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

AD-5591 (AD5591) is a potent, selective, new generation small molecule ALDH2 activator, has the improved biological activities and pharmacological properties compared to Alda-1. AD-5591 (100  μM) significantly increases the enzymatic activity of recombinant WT and mutant human ALDH2 proteins. AD-5591 is the active form of AD-9308.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

1. Chang YC, et al. Nat Commun. 2023 Sep 25;14(1):5971.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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