DC Chemicals · Product datasheet

LTGO-33 — Datasheet

CAT. NO. DC73683

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ParameterValue
Chemical NameLTGO-33
CAS No.2834106-06-6
SynonymsLTGO33;LTGO 33
FormulaC21H17F4N3O3S
M.Wt467.44
SMILESCC1=C(OC2=NC=C(C(F)(F)F)C=C2C(=O)NC2=CC=CC([S@](C)(=N)=O)=C2)C=CC(F)=C1
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

LTGO-33 is a potent, selective inhibitor of voltage-gated sodium channel NaV1.8 with IC50 of 44 nM (hNaV1.8), 600-fold selectivity against NaV1.1-NaV1.7 and NaV1.9.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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