DC Chemicals · Product datasheet

Tenovin-3 — Datasheet

CAT. NO. DC7314

Product page and current package options

ParameterValue
Chemical Name1-(4-AMino-phenyl)-3-(4-tert-butyl-benzoyl)-thiourea
CAS No.1011301-27-1
SynonymsTenovin 3,Tenovin3
FormulaC18H21N3OS
M.Wt327.44384
SMILESCC(C)(C)C1=CC=C(C=C1)C(=O)NC(=S)NC2=CC=C(C=C2)N
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Tenovin-3 is able to increase p53 levels, determined in MCF-7 cells treated for 6 hr at 10 μM.Target: p53in vitro: Tenovins inhibit the activities of human SirT1 and SirT2, two members of the NAD+-dependent class III histone deacetylases that also belong to the sirtuin family.[1]

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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