Rigosertib sodium Datasheet | DC7265

Rigosertib sodium — Datasheet

CAT. NO. DC7265

Parameter	Value
Chemical Name	Rigosertib sodium
CAS No.	1225497-78-8
Synonyms	Rigosertib
Formula	C21H24NNaO8S
M.Wt	473.48
SMILES	COc1cc(OC)c(C=CS(=O)(=O)Cc2ccc(OC)c(NCC(=O)[O-])c2)c(OC)c1.[Na+]
Purity	>98%
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Chemical identity references

Rigosertib sodium identity reference
PubChem chemical identity record

Biological Activity

Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM; shows 30-fold greater selectivity against PLK2 and no activity to PLK3.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.