DC Chemicals · Product datasheet

ML 161 — Datasheet

CAT. NO. DC7197

Product page and current package options

ParameterValue
Chemical Name2-Bromo-N-(3-butyramidophenyl)benzamide
CAS No.423735-93-7
Synonyms2-Bromo-N-(3-butyramidophenyl)benzamide;ML 161;2-bromo-N-[3-(butanoylamino)phenyl]benzamide;ML-161;2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]-benzamide;ML161;2-Bromo-N-[3-[(1-oxobutyl)amino]phenyl]benzamide;2-bromo-N-[3-(butyrylamino)phenyl]benzamide;AK142591;SMR000193713;MLS000571703;Cambridge id 5946339;Oprea1_852187;MLS002699906;ARONIS27179;AOB1565;DFOVLSMXPWPCFH-UHFFFAOYSA-N;HMS3651N10;BENZAMIDE, 2-BROMO-N-[3-[(1-OXOBUTYL)AMINO]PHENYL]-;HMS2461M06;BC;Parmodulin 2;2-bromo-N-[3-(1-oxobutylamino)phenyl]benzamide;BENZAMIDE, 2-BROMO-N-[3-[
FormulaC17H17BrN2O2
M.Wt361.2331
SMILESBrC1=C([H])C([H])=C([H])C([H])=C1C(N([H])C1=C([H])C([H])=C([H])C(=C1[H])N([H])C(C([H])([H])C([H])([H])C([H])([H])[H])=O)=O
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Parmodulin 2 (ML161),a probe, is an allosteric inhibitor of protease-activated receptor 1 (PAR1) with an IC50 of 0.26 μM. Parmodulin 2 inhibits platelet aggregation induced by a PAR1 peptide agonist or by thrombin and has shown cytoprotective effects[1, 2].

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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