DC Chemicals · Product datasheet

Ki16425 — Datasheet

CAT. NO. DC7179

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ParameterValue
Chemical Name3-(4-[4-([1-(2-Chlorophenyl)ethoxy]carbonylamino)-3-methyl-5-isoxazolyl]benzylthio)propanoic acid
CAS No.355025-24-0
Synonyms3-((4-(4-(((1-(2-Chlorophenyl)ethoxy)carbonyl)amino)-3-methylisoxazol-5-yl)benzyl)thio)propanoic acid;Ki16425;3-[[[4-[4-[[[1-(2-CHLOROPHENYL)ETHOXY]CARBONYL]AMINO]-3-METHYL-5-ISOXAZOLY]PHENYL]METHYL]THIO]-PROPANOIC ACID;3-[[4-[4-[1-(2-chlorophenyl)ethoxycarbonylamino]-3-methyl-1,2-oxazol-5-yl]phenyl]methylsulfanyl]propanoic acid;KI-6425;cc-102;CHEMBL361501;CTK8F0787;Ki-16425,;Ki-16425, Ki16425;S1315_Selleck;SureCN3841276;3-[[[4-[4-[[[1-(2-Chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]-propanoic acid;3-[[[4-[4-[[[1-(2-Chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]phenyl]methyl]thio]propanoic acid;Ki 16425;3-[({4-[4-({[1-(2-chlorophenyl)ethoxy]carbonyl}amino)-3-methyl-1,2-oxazol-5-yl]phenyl}methyl)sulfanyl]propanoic acid;MLS006010196;GTPL2907;HMS3654H15;AOB33750;BCP01848;s1315;A;3-(4-[4-([1-(2-Chlorophenyl)ethoxy]carbonylamino)-3-methyl-5-isoxazolyl]benzylthio)propanoic acid
FormulaC23H23ClN2O5S
M.Wt474.9571
SMILESClC1=C([H])C([H])=C([H])C([H])=C1C([H])(C([H])([H])[H])OC(N([H])C1C(C([H])([H])[H])=NOC=1C1C([H])=C([H])C(C([H])([H])SC([H])([H])C([H])([H])C(=O)O[H])=C([H])C=1[H])=O
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Ki16425 is a subtype-selective, competitive antagonist of the EDG-family receptors, LPA1 and LPA3 with Kis of 0.34 μM and 0.93 μM, respectively.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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