Biological Activity
NSI-189 is a nootropic and neurogenic research chemical derived from nicotinamide and pyrazine.
In Vitro
NSI-189 has been shown to stimulate neurogenesis of human hippocampus-derived neural stem cells in vitro and in vivo. The hippocampus is responsible for the consolidation of information from short-term memory to long-term memory, along with spatial navigation [1] [2].
In Vivo
NSI-189 has been shown to increase the hippocampal volume of healthy adult mice by 20% [3].
References & source
Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.