DC Chemicals · Product datasheet

CFTR Inhibitor II — Datasheet

CAT. NO. DC7039

Product page and current package options

ParameterValue
Chemical NameGlycine, N-2-naphthalenyl-, [(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide
CAS No.328541-79-3
SynonymsGlycine, N-2-naphthalenyl-, [(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide;N-2-Naphthalenyl-glycine 2-[(3,5-Dibromo-2,4-dihydroxyphenyl)methylene]hydrazide;CFTR Inhibitor II;CFTR Inhibitor II, GlyH-101;GLYH 101;GlyH-101;N'-[(3,5-dibromo-4-hydroxy-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]-2-(naphthalen-2-ylamino)acetohydrazide;N-2-Naphthalenyl-gly;N-2-Naphthalenylglycine [(3,5-dibromo-2,4-dihydroxyphenyl)methylene]hydrazide
FormulaC19H15N3O3Br2
M.Wt493.1487
SMILESO=C(N/N=C/C1=CC(Br)=C(O)C(Br)=C1O)CNC2=CC3=CC=CC=C3C=C2
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR with Ki of 1.4 uM.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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