DC Chemicals · Product datasheet

Nedisertib (Synonyms: Peposertib; M3814) — Datasheet

CAT. NO. DC70085

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ParameterValue
Chemical NameM-3814
CAS No.1637542-33-6
Synonymsnedisertib;peposertib;M3814;MSC2490484A;GN429E725A;(S)-(2-chloro-4-fluoro-5-(7-morpholinoquinazolin-4-yl)phenyl)(6-methoxypyridazin-3-yl)methanol;(S)-[2-chloro-4-fluoro-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-(6-methoxypyridazin-3-yl)methanol;Nedisertib [INN];nedisertib (deleted INN);GTPL9766;BDBM315715;MSC 2490484A;NSC802822;NSC816960;US10172859, Example 136;MSC 2490484A [W;HY-101570;PEPOSERTIB [WHO-DD];example 136 [WO2014183850];PEPOSERTIB [INN];M-3814(nedisertib);CS-0021723;DA-65178;M 3814;peposertibum;(~{S})-[2-chloranyl-4-fluoranyl-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-(6-methoxypyridazin-3-yl)methanol;3-Pyridazinemethanol, alpha-(2-chloro-4-fluoro-5-(7-(4-morpholinyl)-4-quinazolinyl)phenyl)-6-methoxy-, (alphaS)-;EX-A1679;3-PYRIDAZINEMETHANOL, .ALPHA.-(2-CHLORO-4-FLUORO-5-(7-(4-MORPHOLINYL)-4-QUINAZOLINYL)PHENYL)-6-METHOXY-, (.ALPHA.S)-;UNII-GN429E725A;(S)-(2-chloro-4-fluoro-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl)-(6-methoxypyridazin-3-yl)methanol;NSC-816960;SCHEMBL16235559;MSC 2490484A [WHO-DD];CHEMBL4297629;1637542-33-6;1IX;M-3814;NSC-802822;example 136 (WO2014183850);MSC-2490484A;TS-10640
FormulaC24H21ClFN5O3
M.Wt481.9066
SMILESClC1C=C(C(=CC=1[C@@H](C1C=CC(=NN=1)OC)O)C1C2C=CC(=CC=2N=CN=1)N1CCOCC1)F
Purity98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Nedisertib (M3814, MSC2490484A) is a highly potent, selective, orally bioavailable inhibitor of DNA-PK.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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