DC Chemicals · Product datasheet

SB405483 — Datasheet

CAT. NO. DC67996

Product page and current package options

ParameterValue
Chemical NameSB405483
SynonymsSB405483; SB-405483; SB 405483
FormulaC20H16N4O3
M.Wt360.37
SMILESO=C(NC1=C(O)C=C(C#N)C=C1)NC(N=CC=C2)=C2OCC3=CC=CC=C3
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

SB-405483 is a specific small-molecule chemical compound used in scientific research as an allosteric ligand for the protein cereblon (CRBN). It is primarily a biochemical tool for studying protein degradation pathways and has potential implications for drug discovery.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

Dippon VN, et al. Identification of an allosteric site on the E3 ligase adapter cereblon. Nature. Published online January 21, 2026.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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